RenewaCell Serum

The serum built for menopausal skin. Firmer, smoother, more even-looking skin in a matter of weeks, or your money back.
Visibly firms and smooths skin that lost its bounce after menopause
Powered by patented goji berry stem cell exosomes
Replenishes NAD+, the cellular fuel that drops as we age
Formulated for sensitive, reactive mature skin

Try it risk free for 100 days. If you do not see a visible difference, you get your money back.

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Aislyn Nelson, MD PhD

Aislyn Nelson, MD PhD

As a board-certified dermatologist, I love products that focus on active ingredients. RenewaCell Serum combines peptides, exosomes, NAD+, niacinamide and Mandolione, plus several other active ingredients, to create a serum that addresses not only fine lines but also firmness, radiance and cell renewal. Skin care does not have to be an 11 step process; for my patients, I recommend RenewaCell Serum.

Frequently Asked

Menopause does not just dry your skin out. It shuts down three things at once underneath it.
Your skin cells stop passing signals to each other. The fuel they run on runs low. And collagen falls off a cliff, up to 30% of it gone in the first five years after menopause.
That is why the creams stopped working. They sit on the surface. The problem is three layers down.
RenewaCell was built to answer all three at once.

  • Patented goji berry stem cell exosomes help restore cell-to-cell communication.
  • NAD+ replenishes the cellular energy that declines with age.
  • Matrixyl® 3000, the most studied peptide complex in skincare, helps support collagen synthesis for firmer-looking skin.

Two to four drops, once or twice a day. That is the whole routine.

  • 1 Cleanse. Start on clean, dry skin.
  • 2 Apply. Two to four drops. Face, neck and chest.
  • 3 Massage. Gently press and sweep upward until absorbed.
  • 4 Follow. Moisturiser on top, morning or evening or both.

PS: Works beautifully on its own. Pair it with RenewaLift for deeper, faster visible results.

Menopausal skin gets thinner, drier and more reactive. We formulated around that from the start.
RenewaCell is built on a clean, biocompatible water base with birch juice, sea water, glycerin and multiple humectants. It is lightweight and non-greasy.
No parabens, no formaldehyde-releasing preservatives, no harsh additives, no fragrance.
Most women feel nothing but a light cool finish. As with anything new, patch test first and check the ingredient list if you have known sensitivities.

Fragrance free
Paraben free
Cruelty free
Formaldehyde-donor free

Face, neck and chest. Anywhere menopause is showing up on the surface.
Used consistently, most women notice a smoother, firmer, more even-looking complexion within a matter of weeks.

Each RenewaCell Serum is a 30ml airless pump bottle. At two to four drops a day, one bottle is a one month supply.

  • 1 Month Supply: 1 bottle of RenewaCell Serum
  • 2 Month Supply: 2 bottles, plus all 3 free gifts
  • 3 Month Supply: 3 bottles, plus all 3 free gifts

The airless pump keeps the actives stable and sealed from air, so the last drop is as potent as the first.
PS: Every order comes with a short video guide on getting the most out of each bottle.

We are confident in what this formula does, which is why the risk sits with us and not with you.
Use RenewaCell for 100 days. If you do not see a visible difference in your skin's firmness, smoothness and tone, contact us and we will refund you in full. No hassle, no questions asked.
The guarantee covers every bottle in your order, not just the first one.

Free shipping on every order.
Processing time: 1 to 2 business days
Shipping time, USA: 2 to 5 business days
Shipping time, international: 4 to 7 business days
Unopened items can be returned within 30 days of delivery in their original condition. Opened bottles are covered by the 30 Day Money Back Guarantee above. See our full return policy for details.

Real Women, Real Results

Excellent Excellent Trustpilot rating 100,000+ Happy Customers

Based on individual user experience. Results may vary.

Recommended By US Board-Certified Dermatologists

Recommendation from Ellen Turner, MD
Recommendation from Aislyn Nelson MD PhD

Why Menopausal Skin Stops Responding To Everything You Try

It is not that you picked the wrong cream. It is that menopause changed the problem, and nothing on the surface can reach it.

Woman looking at menopausal skin concerns in the mirror

1. The signal goes quiet

Your skin cells talk to each other constantly. Repair here. build collagen there. hold moisture. After menopause, those signals thin out. The cells are still there. They just stop hearing each other.

2. The fuel runs out

NAD+ is the energy currency your skin cells run on. Levels fall as we age. Without it, cells cannot do the work of rebuilding and holding onto moisture, and skin starts to look flat and depleted.

3. Collagen falls off a cliff

Women lose up to 30% of their skin collagen in the first five years after menopause. Not gradually. That is the drop that takes your firmness and your bounce with it.

How RenewaCell Answers All Three

Illustration showing cell-to-cell communication

Restore the signal

PhytoCellTec™ Exosomes 0.1% Concentration, a patented plant-based exosome complex from goji berry stem cells, helps support cell-to-cell communication and skin's natural renewal process.

Illustration of a skin cell

Refuel the cell

NAD+ delivered topically, an ingredient more commonly found in prestige and clinical skincare, supports skin's energy systems for improved resilience and appearance.

Illustration representing skin structure and collagen support

Rebuild the structure

Matrixyl® 3000, the most studied peptide complex in skincare, helps support collagen synthesis and visibly improve firmness and smoothness over time.

How To Use — 4 Simple Steps

Two minutes, twice a day

Cleanse skin before applying RenewaCell

1 Cleanse

Start on clean, dry skin. Morning, evening, or both.

Apply RenewaCell serum

2 Apply

Two to four drops. Face, neck and chest.

Massage RenewaCell into the skin

3 Massage

Press and sweep upward until fully absorbed. No tugging.

Finish the routine with moisturiser or sunscreen

4 Seal

Moisturiser or sunscreen on top. Done.

Woman holding RenewaCell Serum

Powerful Ingredients, Scientifically Backed

What's inside and why it matters.

Powerful Ingredients, Scientifically Backed

Dermatologist Recommended

Made In The USA

Cruelty Free

Paraben & Formaldehyde-Donor Free

100 Day Money Back Guarantee

100 Day Money Back Guarantee

Try It Risk Free for 100 Days

Science, dermatologists and 100,000+ women agree. That is why the risk stays with us.

Use RenewaCell for 100 days. If you do not see a visible difference in your skin's firmness, smoothness and tone, contact us and we will refund you in full. Every bottle in your order, not just the first.

Get RenewaCell Risk Free

What Our Customers Are Saying

Debra
Debra Verified Customer

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Debra
Debra Verified Customer

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Frequently Asked Questions

Each bottle is 30ml in an airless pump. At two to four drops a day, that is a one month supply. The airless pump seals the actives from air, so the last drop works as well as the first.

100 Day Guarantee

Try it risk free. See a visible difference or get your money back.

Dermatologist Recommended

Recommended by US board-certified dermatologists.

Free shipping

Free shipping on every order, with 2 to 5 day US delivery.

Real Human Support

Our team is here to help, seven days a week.