Trusted by 100,000+ women over 50
Trusted by 100,000+ women over 50
Renewa AgeDefy Serum
A lightweight, fast-absorbing serum powered by niacinamide, a tri-peptide complex, and a fermented botanical blend to help skin look firmer, smoother, more even-toned, and more radiant.
Renewa AgeDefy Serum is a lightweight, fast-absorbing formula made with aging and sensitive skin in mind. It combines niacinamide with a tri-peptide complex, hydrating hyaluronic acid and snow mushroom, and a fermented botanical antioxidant blend to help skin look firmer, smoother, more even-toned, and more radiant.
Key ingredients:
- Niacinamide (Vitamin B3), which helps visibly reduce the look of uneven tone and dullness for a brighter, more even-looking complexion.
- Tri-Peptide Complex (Oligopeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4), which helps visibly smooth the look of expression lines and supports the appearance of firmer, more resilient-looking skin.
- Sodium Hyaluronate & Tremella (Snow Mushroom) Polysaccharide, which attract and hold moisture to help skin look plumper and smoother.
- Fermented Botanical Blend (including Centella Asiatica, Purslane, Black Bamboo, and Lactobacillus/Soybean Ferment), which helps support a more even-looking, radiant, and resilient complexion.
Designed to work beautifully on its own or alongside your Renewa LED or microcurrent tools, helping your serum glide on and absorb for a smoother, more refreshed look.
- Begin with clean, dry skin—face, neck, or décolletage.
- Apply a few drops of AgeDefy Serum and gently massage until fully absorbed.
- For enhanced results, pair with Renewa tools like RenewaLift, LuminaGlow, or EyeLift—tools help enhance absorption for better results.
- Use daily, morning and/or night.
- Follow with moisturizer or sunscreen to lock in hydration.
Many people notice their skin looks smoother, more even-toned, and more hydrated within 2 to 3 weeks of consistent use. Pairing it with your Renewa tool can help the serum glide on and absorb. Individual results vary based on skin type, routine, and consistency.
Note: Individual results will vary based on skin type, routine, and consistency.
Intended Use
Renewa AgeDefy Serum is a cosmetic skincare product for external use only. It is not a drug or medical product and is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Statements on this page have not been evaluated by the U.S. Food and Drug Administration. Individual results vary.
Do Not Use If You:
- have a known allergy or sensitivity to any ingredient listed on this page or on the packaging
- have open wounds, cuts, or broken, sunburned, infected, or inflamed skin in the application area
- have had a reaction to this product before
Ask a Doctor Before Use If You:
- are pregnant or nursing
- have eczema, rosacea, psoriasis, dermatitis, or another chronic skin condition
- are under a dermatologist’s care or using prescription skin treatments
- have recently had a chemical peel, laser, or other professional skin procedure
Patch Test Required
Before first use, apply a small amount to the inner forearm or behind the ear and wait 24 hours. Do not use the product if redness, itching, burning, or swelling occurs.
When Using This Product
Avoid contact with eyes and mucous membranes. If contact occurs, rinse thoroughly with water. Stop use and ask a doctor if irritation, rash, or swelling develops and persists. Keep out of reach of children.
Refund Eligibility
For health and safety reasons, this product is non-returnable and not eligible for a refund. Please review the full ingredient list and all warnings before purchasing.
For full safety information, warnings, and disclosures, please visit https://www.tryrenewa.com/pages/product-disclosures.
Three Peptides. One Firmer, Smoother Face.
A triple peptide complex teams up with Niacinamide and a probiotic ferment to work on every early sign of aging at once.
Women notice fine lines and expression lines look softer, skin feels firmer, and dull, uneven tone gives way to a brighter, more even glow over a few weeks. Deep hydration keeps skin plump all day.
RenewaLift Customer Transformations
Fine Lines and Uneven Texture
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Helps soften the appearance of stubborn wrinkles
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Supports smoother-looking skin
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Easy to include in a daily routine
I first noticed my wrinkles when looking at photographs from my daughter’s wedding. After using AgeDefy consistently for several weeks, my skin began to look smoother and more refreshed. It has become one of the easiest steps in my routine.
Loss of Firmness
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Helps skin look firmer and more toned
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Lightweight alternative to heavy creams
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Leaves mature skin feeling nourished
I had already tried several expensive serums and creams, but I wanted something lightweight that still made my skin feel cared for. AgeDefy absorbs beautifully and helps my complexion look firmer, smoother, and more refreshed.
Dry Sagging-Looking Skin
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Helps improve the look of wrinkles and texture
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Comfortable for regular use
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Pairs beautifully with RenewaLift
I’ve been using AgeDefy Serum with my RenewaLift and have noticed an improvement in the way my wrinkles and sagging-looking areas appear. I also love that it leaves my skin feeling hydrated without making it oily.
How It Works
Renewa AgeDefy Serum combines targeted age-supporting ingredients with lightweight, long-lasting hydration to help improve the appearance of fine lines, uneven texture, dullness, and loss of firmness.
A concentrated 5% niacinamide blend helps support the skin’s natural moisture barrier while visibly improving uneven-looking tone, enlarged pores, and rough texture. Hyaluronic acid and glycerin attract and retain moisture, helping dry, crepey-looking skin appear plumper, smoother, and more supple.
Panax ginseng extract helps revitalize tired-looking skin, while an antioxidant complex supports the complexion against environmental stressors that can contribute to visible signs of premature aging.
Transform Your Skin in 4 Simple Steps
We recommend daily use, both morning and night, for visible results.
Cleanse Your Skin
Apply The Renewa AgeDefy Serum
Massage the serum into your skin or pair it with RenewaLift or EyeLift.
Massage the serum into your skin or pair it with RenewaLift or EyeLift.
Powerful Technology That Brings Visible Results
Niacinamide
Hyaluronic Acid
Tri-Peptide Complex
Centella Asiatica
Formulated By Experts,
Recommended By Dermatologists
As a board-certified dermatologist, I'm selective about the skincare and at-home treatments I recommend, and Renewa Skin's products are ones I trust. Their formulas are thoughtfully developed to help deliver visible, real results with consistent use.
— Ellen Turner, MD
US Board-Certified Dermatologist
Dr. Turner and Dr. Nelson are compensated partners of Renewa Skin who have personally evaluated our products.
See Visible Results Or Get Your Money back With Our 100-Day Satisfaction Guarantee
At Renewa Skin, we stand behind our products. That's why we offer a 100-Day Satisfaction Guarantee.
Try the Serum for a full 100 days, and if you're not fully satisfied, contact us and we will make it right.
Frequently Asked Questions
Renewa AgeDefy Serum combines niacinamide with a tri-peptide complex, hydrating hyaluronic acid and snow mushroom, and a fermented botanical antioxidant blend, all designed to help skin look firmer, smoother, more even-toned, and more radiant. It's lightweight, fast-absorbing, and works beautifully alone or paired with Renewa's LED and microcurrent tools.
AgeDefy Serum is specifically formulated with sensitive and mature skin in mind. It contains no harsh actives, artificial fragrances, or unnecessary fillers. The gentle formula is designed to hydrate and nourish. As with any skincare, discontinue use if you experience discomfort or irritation.
Many users report noticeably smoother, more hydrated skin within the first few uses. With consistent daily use, you may see improvements in firmness, fine lines, and overall radiance within 3–4 weeks. For best results, use morning and night, and consider pairing with Renewa tools. Individual results vary based on skin type and consistency.
Absolutely! AgeDefy Serum was made to complement Renewa's LED and microcurrent tools. Apply the serum before using your tool—it enhances conductivity and helps the active ingredients absorb more effectively.
Using AgeDefy Serum is simple: 1. Start with clean, dry skin. 2. Apply a few drops to your face, neck, and décolletage. 3. Gently massage until fully absorbed. 4. For enhanced results, use with your Renewa tool. 5. Follow with moisturizer or sunscreen. Use daily, morning and/or night, for best results.
Our formula centers on four things: Niacinamide (Vitamin B3) to help improve the appearance of uneven skin tone and texture; a Tri-Peptide Complex (Oligopeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4) to help visibly smooth the look of expression lines and support firmer-looking skin; Sodium Hyaluronate and Tremella (Snow Mushroom) Polysaccharide to deliver long-lasting hydration and plumpness; and a Fermented Botanical Blend (including Centella Asiatica, Purslane, and Black Bamboo) to help support a more radiant, even-looking complexion.
Full Ingredient List: Aqua, Glycerin, Butylene Glycol, PEG/PPG-17/6 Copolymer, 1,2-Hexanediol, Hydroxyacetophenone, Niacinamide, Lactobacillus/Soybean Ferment Filtrate, Sodium Hyaluronate, Dipropylene Glycol, Tremella Fuciformis Polysaccharide, 1,2-Pentanediol, Centella Asiatica Extract, Passiflora Incarnata Extract, Houttuynia Cordata Extract, Eclipta Prostrata Extract, Phyllostachys Nigra Leaf Extract, Polygonum Multiflorum Root Extract, Urtica Dioica Extract, Disodium EDTA, Portulaca Oleracea Extract, Polysorbate 20, Ethylhexylglycerin, Oligopeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4.
Yes! AgeDefy Serum absorbs quickly and creates a smooth, hydrated base for makeup application. Many users find their makeup applies more evenly and lasts longer when used over the serum.
Free shipping on US orders of $49.90+ and international orders of $99+, plus every purchase is backed by our 100-day satisfaction guarantee.
Yes! Every order includes FREE worldwide shipping.