4.5 stars on (915 reviews)
4.5 stars on (915 reviews)

RenewaCell Serum

Advanced skincare for mature skin that deserves more than ordinary anti-aging products.

Powered by goji berry-derived exosome ingredients, peptides, and NAD+, RenewaCell is designed to improve the appearance of firmness, smoothness, and radiance as your skin's needs change with age.

  • Restore the look of firmness: Helps skin appear smoother, firmer, and more supple.
  • Target visible signs of aging: Helps soften the appearance of fine lines and wrinkles.
  • Advanced age-conscious formula: Features patented goji berry-derived exosome ingredients, peptides, and NAD+.
  • Designed for mature skin: Formulated with the needs of delicate, sensitive-looking skin in mind.
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Ingredients

Developed in collaboration with PhD scientists, this USA-made formula combines advanced skincare ingredients selected for the changing needs of mature skin.

Its formulation features:

  • PhytoCellTec™ Exosomes: A patented goji berry-derived complex.
  • Matrixyl® 3000: A clinically studied peptide complex that targets the appearance of fine lines and wrinkles.
  • NAD+: A naturally occurring molecule involved in cellular energy metabolism.
  • Magnolidone®: A mineral-based ingredient designed to support skin hydration and balance.
  • Niacinamide + Vitamin C: Help improve the appearance of uneven skin tone and dullness.
  • Sodium Hyaluronate: Helps attract and retain moisture for plumper-looking skin.
How to Use

After cleansing, apply the serum as directed on the product packaging, then follow with your moisturiser. Confirm the application amount, recommended frequency and other directions against the approved usage instructions.

Benefits

Designed to improve the appearance of fine lines, wrinkles, uneven tone and loss of firmness, while supporting hydration and a smoother, more radiant-looking complexion.

Is It Suitable for My Skin?

RenewaCell was developed with sensitive or reactive skin in mind, including skin that feels dry or delicate. Its lightweight aqueous base is intended to be compatible with mature skin. Patch-test before first use and discontinue if irritation occurs.

The "NO" List

No Added Fragrance: No unnecessary perfumes added to the formula. Ideal for customers who prefer fragrance-free skincare.

No Parabens: Formulated without parabens.

No Formaldehyde-Releasing Preservatives: Made without this category of preservatives.

No Harsh Additives: Thoughtfully formulated with mature skin's needs in mind.

Advanced Ingredients. Visible Skin Benefits.

One advanced formula combining targeted skincare ingredients for firmer-looking, smoother, more hydrated and radiant skin.

Firmer, Revitalized-Looking Skin - after
Firmer, Revitalized-Looking Skin - before

Firmer, Revitalized-Looking Skin

PhytoCellTec™ Exosomes

A patented goji berry-derived complex selected to support healthy-looking, resilient skin.

Reduced wrinkles & fine lines - after
Reduced wrinkles & fine lines - before

Reduced wrinkles & fine lines

Matrixyl® 3000 Peptides

A clinically studied peptide complex that helps improve the appearance of fine lines, wrinkles and firmness.

Glowing, radiant looking skin - after
Glowing, radiant looking skin - before

Glowing, radiant looking skin

NAD+

A naturally occurring molecule involved in cellular energy metabolism, included in RenewaCell's advanced skincare formula.

Plumper, More Hydrated Skin - after
Plumper, More Hydrated Skin - before

Plumper, More Hydrated Skin

Sodium Hyaluronate + Sodium PCA

Moisture-binding ingredients that help skin retain hydration for a softer, plumper-looking complexion.

Brighter, More Even-Looking Skin - after
Brighter, More Even-Looking Skin - before

Brighter, More Even-Looking Skin

Niacinamide + Vitamin C

Help improve the appearance of uneven skin tone, dullness and texture for a more radiant-looking complexion.

Smoother, tighter skin - after
Smoother, tighter skin - before

Smoother, tighter skin

BarPull® G

A film-forming active that provides an immediate tightening sensation for a smoother-looking finish.

  • Patented Skincare Actives
  • Developed with PhD Scientists
  • Made in the USA

Recommended By US Board-Certified Dermatologists

Ellen Turner, MD

As a board-certified dermatologist, I’m selective about the at-home devices I suggest, and Renewa is one I’m comfortable recommending. It’s a well-engineered option for anyone looking to support their at-home skincare routine.

— Ellen Turner, MD

US Board-Certified Dermatologist

Aislyn Nelson, MD PhD

"As a board-certified dermatologist, I love products that focus on active ingredients. RenewaCell Serum combines peptides, exosomes, NAD+, niacinamide and Mandolione, plus several other active ingredients, to create a serum that addresses not only fine lines but also firmness, radiance and cell renewal. Skin care does not have to be an 11 step process; for my patients, I recommend RenewaCell Serum."

— Aislyn Nelson, MD PhD

US Board-Certified Dermatologist

Real woman, Real Results

  • 84%

    of surveyed customers reported firmer-looking skin after using RenewaCell

  • 81%

    of surveyed customers reported smoother skin with softer-looking fine lines

  • 79%

    of surveyed customers reported brighter skin and a more even-looking tone

  • 88%

    reported better results than the creams and serums they used before

Powerful Ingredients, Scientifically Backed

  • Developed With PhD Scientists

  • Made in the USA

  • Cruelty Free

  • No Parabens or Formaldehyde Donors

  • 100-Day Money-Back Guarantee

100-day money-back guarantee

You’re Protected By Our 100 Day Money-Back Guarantee

We're confident you'll see a visible difference in your wrinkles, skin tone and firmness that you can try it for over three months to make sure it works for you. If for any reason it doesn’t we'll make it right with a full no hassle refund. Try RenewaCell for 100 days. If you're not satisfied, contact us for a full refund. Because we want you to shop with confidence.

See our full Returns & Refund Policy.

What Our Customers Are Saying

Debra
Debra Verified Customer
★ ★ ★ ★ ★

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer
★ ★ ★ ★ ★

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer
★ ★ ★ ★ ★

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer
★ ★ ★ ★ ★

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer
★ ★ ★ ★ ★

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer
★ ★ ★ ★ ★

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer
★ ★ ★ ★ ★

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer
★ ★ ★ ★ ★

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Debra
Debra Verified Customer
★ ★ ★ ★ ★

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer
★ ★ ★ ★ ★

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer
★ ★ ★ ★ ★

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer
★ ★ ★ ★ ★

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer
★ ★ ★ ★ ★

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer
★ ★ ★ ★ ★

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer
★ ★ ★ ★ ★

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer
★ ★ ★ ★ ★

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Frequently Asked Questions

Most serums treat the surface so it never touches the real cause of dryness, dullness or wrinkles and fine lines for changing menopausal skin. RenewaCell targets the three biological changes that cause quicker aging in menopausal skin: the breakdown in cell-to-cell communication, the depletion of cellular energy, and the acceleration of collagen loss that menopause triggers. Exosomes, Peptides, and NAD+ absorb into the deeper layers of skin to work at the cellular level where the skin aging actually starts.