Why Menopausal Skin Stops Responding To Everything You Try

Skin Cell Communication Breaks Down

Your skin cells send fewer repair signals to each other over time. No matter what you apply on top, the internal coordination that supports collagen production, skin barrier health, and firmness slows down.

Skin Cellular Energy Runs Out

NAD+, the fuel your skin cells run on, can decline by as much as 50% as we age. Without it, cells struggle to repair, rebuild, and retain moisture, leaving skin visibly dull and depleted.

Severe Collagen Loss

Women lose 30% of their skin collagen in the first five years of menopause. The decline of collagen gets worse over time, leading to deeper wrinkles and worse sagging.

How RenewaCell Turns Back The Clock On Menopausal Skin

Results After 28 Days Of RenewaCell

  • Many Women Reported Visibly Firmer Skin Within Two Weeks
  • Many Women Notice Deep Wrinkles Are Noticeably Softer And Shallower
  • Many Women Report Plumper, Hydrated Skin That Glows All Day

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Recommended By US Board-Certified Dermatologists

Dermatologist recommended Ellen Turner, MD

After just four weeks of using RenewaCell Serum, I've been amazed by the difference in my skin. As a double-board certified dermatologist, I'm selective about the products I use and recommend, which is why l'm particularly impressed by RenewaCell's combination of exosomes, peptides, and NAD+. RenewaCell is one of those rare products that has earned a permanent place in my skincare routine.

— Ellen Turner, MD US Board-Certified Dermatologist
Dermatologist recommended Aislyn Nelson, MD PhD

As a board-certified dermatologist, I love products that focus on active ingredients. RenewaCell Serum combines peptides, exosomes, NAD+, niacinamide and Mandolione, plus several other active ingredients, to create a serum that addresses not only fine lines but also firmness, radiance and cell renewal.  Skin care does not have to be an 11 step process; for my patients, I recommend RenewaCell Serum.

— Aislyn Nelson, MD PhD US Board-Certified Dermatologist

Dr. Turner and Dr. Nelson are compensated partners of Renewa Skin who have personally evaluated our products.

Developed with PhD Scientists

Dermatologist Recommended

Made In The USA

Non-GMO

100-Day Money-Back Guarantee

100,000+ Happy Customers

How To Use RenewaCell For the Best Results

Works on its own, but quicker results when paired with RenewaLift.

Use daily morning or evening and follow with moisturizer or SPF.

Consistent daily use produces the best results with noticeable visible changes within 2 to 4 weeks.

Woman cleaning and drying her skin
Step 1

Clean and dry your skin Clean and dry your skin

Woman applying RenewaCell serum drops
Step 2

Two to four drops. Face, neck and chest. Apply 2 to 4 drops and gently massage in

Woman applying RenewaCell in upward motions
Step 3

Press and sweep upward until fully absorbed Press and sweep upward until fully absorbed

Woman gently patting skincare into her face
Step 4

Gently Pat Until Absorbed Gently Pat Until Absorbed

Why Women Are Raving About RenewaCell

RenewaCell Serum

Developed with PhD scientists. RenewaCell combines Exosomes, Peptides, and NAD+ to help stimulate collagen production, support cellular resilience, and restore the look of firmness, hydration, and radiance that menopause can take a toll on.
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Ellen Turner, MD

After just four weeks of using RenewaCell Serum, I've been amazed by the difference in my skin. As a double-board certified dermatologist, I'm selective about the products I use and recommend, which is why l'm particularly impressed by RenewaCell's combination of exosomes, peptides, and NAD+. RenewaCell is one of those rare products that has earned a permanent place in my skincare routine.

Ellen Turner, MD

Double Board-Certified Dermatologist

  • Firmer, plumper, visibly smoother skin in 28 days
  • Deeply hydrated and glowing skin all day
  • Fine lines visibly smooth and soften over time
  • Fades dark spots for brighter, even skin tone
  • Strengthens the skin barrier against daily damage
Description
  • RenewaCell Serum is a clinically formulated daily serum designed to rebuild collagen, restore deep hydration, and visibly firm menopausal skin. Developed with PhD scientists and recommended by dermatologists.
  • Exosomes (Lycium Barbarum Callus / Cell Culture Extract) restart the cell-to-cell communication menopause disrupts, signaling skin to produce collagen, retain moisture, and repair damage from the inside out for denser skin with less wrinkles.
  • Peptides (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7) trigger collagen rebuilding and are clinically shown to reduce wrinkles by up to 45% and improve skin firmness.
  • NAD+ (Nicotinamide Adenine Dinucleotide) restores the cellular energy that drops by 50% during menopause to increase collagen synthesis, and rescue dark spots.

RenewaCell is designed for sensitive menopausal and perimenopausal skin to visibly firm the jaw and cheeks, restore lost radiance, resolve chronic dryness, and fill lines from the inside out in 28 days of consistent daily use.

How to use
  1. Start with clean dry skin.
  2. Apply 2 to 4 drops of RenewaCell Serum and gently massage in.
  3. For enhanced results, follow immediately with RenewaLift.
  4. Finish with your moisturizer or SPF.

Use daily morning or evening. Consistent daily use produces the best results and most women notice visible changes within 2 to 4 weeks.

When will I see results?
  • Most women notice softer and more hydrated skin within the first week.
  • Visible improvements in radiance, firmness, wrinkles and dark spots typically appear between weeks 2 and 4.
  • Full structural results like a firmer jawline, fuller cheeks and visibly denser skin develop with consistent use over 6 to 8 weeks.

Individual results vary, and daily consistent use is key.

100-day money-back guarantee

You’re Protected By Our 100 Day Money-Back Guarantee

We're confident you'll see a visible difference in your wrinkles, skin tone and firmness that you can try it for over three months to make sure it works for you. If for any reason it doesn’t we'll make it right with a full no hassle refund. Try RenewaCell for 100 days. If you're not satisfied, contact us for a full refund. Because we want you to shop with confidence.

See our full Returns & Refund Policy.

What Our Customers Are Saying

Debra
Debra Verified Customer
★ ★ ★ ★ ★

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer
★ ★ ★ ★ ★

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer
★ ★ ★ ★ ★

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer
★ ★ ★ ★ ★

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer
★ ★ ★ ★ ★

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer
★ ★ ★ ★ ★

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer
★ ★ ★ ★ ★

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer
★ ★ ★ ★ ★

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Debra
Debra Verified Customer
★ ★ ★ ★ ★

I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.

Suzanne
Suzanne Verified Customer
★ ★ ★ ★ ★

I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.

Shelly
Shelly Verified Customer
★ ★ ★ ★ ★

Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.

Viven
Viven Verified Customer
★ ★ ★ ★ ★

I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.

Lorrie
Lorrie Verified Customer
★ ★ ★ ★ ★

What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!

Sarah D.
Sarah D. Verified Customer
★ ★ ★ ★ ★

I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.

Andrea
Andrea Verified Customer
★ ★ ★ ★ ★

I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.

Anna M.
Anna M. Verified Customer
★ ★ ★ ★ ★

I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.

Frequently Asked Questions

Most serums treat the surface so it never touches the real cause of dryness, dullness or wrinkles and fine lines for changing menopausal skin. RenewaCell targets the three biological changes that cause quicker aging in menopausal skin: the breakdown in cell-to-cell communication, the depletion of cellular energy, and the acceleration of collagen loss that menopause triggers. Exosomes, Peptides, and NAD+ absorb into the deeper layers of skin to work at the cellular level where the skin aging actually starts.