Why Menopausal Skin Stops Responding To Everything You Try
Skin Cell Communication Breaks Down
Your skin cells send fewer repair signals to each other over time. No matter what you apply on top, the internal coordination that supports collagen production, skin barrier health, and firmness slows down.
Skin Cellular Energy Runs Out
NAD+, the fuel your skin cells run on, can decline by as much as 50% as we age. Without it, cells struggle to repair, rebuild, and retain moisture, leaving skin visibly dull and depleted.
Severe Collagen Loss
Women lose 30% of their skin collagen in the first five years of menopause. The decline of collagen gets worse over time, leading to deeper wrinkles and worse sagging.
How RenewaCell Turns Back The Clock On Menopausal Skin
PhytoCellTec™ Exosomes 0.1% Concentration
Renewal / Communication / Radiance
A patented plant-based exosome complex derived from goji berry stem cells, at 0.1% concentration. Helps support the skin's natural cell-to-cell communication and renewal process for a healthier, more refreshed appearance.
NAD+
Cellular Vitality / Resilience / Smoothness
Nicotinamide Adenine Dinucleotide, a bioactive found naturally in skin cells where it plays a central role in cellular energy. Supports skin's energy systems for improved resilience and a more youthful-looking appearance.
Matrixyl® 3000
Firmness / Fine Lines / Structure
A clinically studied peptide duo of Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7. Helps support collagen synthesis and visibly improve skin firmness and smoothness over time.
Magnolidone®
Barrier / Balance / Hydration
A mineral-powered active that helps maintain a clearer, more balanced-looking complexion. Strengthens the skin barrier and helps hold hydration where menopausal skin loses it fastest.
Niacinamide (Vitamin B3)
Even Tone / Pore Refinement / Texture
A multitasking form of vitamin B3 that helps refine the look of pores and improve skin texture. Brightens the look of uneven tone and helps reduce the appearance of fine lines.
Magnesium Ascorbyl Phosphate
Radiance / Brightness / Protection
A stable, gentle form of vitamin C chosen specifically because mature skin does not tolerate the harsh ones. Helps brighten dull skin and improve the appearance of uneven tone.
Sodium Hyaluronate + Sodium PCA
Hydration / Plumping / Comfort
A hydration duo that deeply replenishes moisture and helps skin retain it. Together they help skin look plumper and feel smoother, and they soften the look of fine lines.
Birch Juice + Sea Water
Soothing / Freshness / Minerals
Rich in minerals and nutrients, formulated in to help soothe, hydrate and revitalise. They give the formula its light, comfortable finish on reactive skin.
Results After 28 Days Of RenewaCell
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Many Women Reported Visibly Firmer Skin Within Two Weeks
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Many Women Notice Deep Wrinkles Are Noticeably Softer And Shallower
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Many Women Report Plumper, Hydrated Skin That Glows All Day
Recommended By US Board-Certified Dermatologists
After just four weeks of using RenewaCell Serum, I've been amazed by the difference in my skin. As a double-board certified dermatologist, I'm selective about the products I use and recommend, which is why l'm particularly impressed by RenewaCell's combination of exosomes, peptides, and NAD+. RenewaCell is one of those rare products that has earned a permanent place in my skincare routine.
As a board-certified dermatologist, I love products that focus on active ingredients. RenewaCell Serum combines peptides, exosomes, NAD+, niacinamide and Mandolione, plus several other active ingredients, to create a serum that addresses not only fine lines but also firmness, radiance and cell renewal. Skin care does not have to be an 11 step process; for my patients, I recommend RenewaCell Serum.
Dr. Turner and Dr. Nelson are compensated partners of Renewa Skin who have personally evaluated our products.
Developed with PhD Scientists
Dermatologist Recommended
Made In The USA
Non-GMO
100-Day Money-Back Guarantee
100,000+ Happy Customers
How To Use RenewaCell For the Best Results
Works on its own, but quicker results when paired with RenewaLift.
Use daily morning or evening and follow with moisturizer or SPF.
Consistent daily use produces the best results with noticeable visible changes within 2 to 4 weeks.
Clean and dry your skin Clean and dry your skin
Two to four drops. Face, neck and chest. Apply 2 to 4 drops and gently massage in
Press and sweep upward until fully absorbed Press and sweep upward until fully absorbed
Gently Pat Until Absorbed Gently Pat Until Absorbed
Why Women Are Raving About RenewaCell
Verified Customer
I am 58 and my skin changed faster in two years of menopause than in the twenty before it. Six weeks on RenewaCell and it finally feels like skin again instead of paper. My husband asked what I was doing differently.
Verified Customer
I bought it for the wrinkles. What I actually noticed first was that my skin looked awake. Less flat. This was in the first couple of weeks.
Verified Customer
I use it with my RenewaLift and the two together are doing something neither did alone. My makeup sits properly again instead of settling into every line.
Verified Customer
Three years of perimenopause and nothing touched the dullness and crepey texture. Two months in and there is a glow I have not seen since my early forties.
Verified Customer
Honestly impressed. After one month the sagging on my face and neck has improved significantly! Never expected a serum to do that! Renewa you've gained a fan!
Verified Customer
I have reactive skin and I have reacted to nearly everything. Not this. It goes on light, it does not sting, and my skin is calmer than it has been in years.
Verified Customer
I am four weeks in so I am not going to pretend it is a miracle. But there is a real difference in how firm my neck looks and I am going to keep going.
Verified Customer
I am seventy. I was not expecting to be impressed. My skin looks denser, if that makes sense, and the deep lines around my mouth are not as deep. I am on my third bottle.
RenewaCell Serum
Locked
Locked
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Ellen Turner, MD
Double Board-Certified Dermatologist
Firmer, plumper, visibly smoother skin in 28 days
Deeply hydrated and glowing skin all day
Fine lines visibly smooth and soften over time
Fades dark spots for brighter, even skin tone
Strengthens the skin barrier against daily damage
Description
- RenewaCell Serum is a clinically formulated daily serum designed to rebuild collagen, restore deep hydration, and visibly firm menopausal skin. Developed with PhD scientists and recommended by dermatologists.
- Exosomes (Lycium Barbarum Callus / Cell Culture Extract) restart the cell-to-cell communication menopause disrupts, signaling skin to produce collagen, retain moisture, and repair damage from the inside out for denser skin with less wrinkles.
- Peptides (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7) trigger collagen rebuilding and are clinically shown to reduce wrinkles by up to 45% and improve skin firmness.
- NAD+ (Nicotinamide Adenine Dinucleotide) restores the cellular energy that drops by 50% during menopause to increase collagen synthesis, and rescue dark spots.
RenewaCell is designed for sensitive menopausal and perimenopausal skin to visibly firm the jaw and cheeks, restore lost radiance, resolve chronic dryness, and fill lines from the inside out in 28 days of consistent daily use.
How to use
- Start with clean dry skin.
- Apply 2 to 4 drops of RenewaCell Serum and gently massage in.
- For enhanced results, follow immediately with RenewaLift.
- Finish with your moisturizer or SPF.
Use daily morning or evening. Consistent daily use produces the best results and most women notice visible changes within 2 to 4 weeks.
When will I see results?
- Most women notice softer and more hydrated skin within the first week.
- Visible improvements in radiance, firmness, wrinkles and dark spots typically appear between weeks 2 and 4.
- Full structural results like a firmer jawline, fuller cheeks and visibly denser skin develop with consistent use over 6 to 8 weeks.
Individual results vary, and daily consistent use is key.
You’re Protected By Our 100 Day Money-Back Guarantee
We're confident you'll see a visible difference in your wrinkles, skin tone and firmness that you can try it for over three months to make sure it works for you. If for any reason it doesn’t we'll make it right with a full no hassle refund. Try RenewaCell for 100 days. If you're not satisfied, contact us for a full refund. Because we want you to shop with confidence.
See our full Returns & Refund Policy.What Our Customers Are Saying
I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.
I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.
Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.
I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.
What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!
I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.
I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.
I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.
I looove LOVE this serum! It's really light, almost watery, and it absorbs in seconds. I'm on my second bottle now. The biggest thing I noticed is my skin doesn't look dull anymore. Wrinkles are still there but not as deep lol I'm 56, but my skin looks healthier and my foundation goes on so much smoother.
I have very dry, thin skin since menopause and this is the first serum that hasn't made it feel tight after. It's hydrating without being greasy. I've been using it 7 weeks and the dullness is gone, my skin actually has some glow to it now. Texture is smoother too. Don't expect it to erase deep wrinkles, but for overall skin quality it's the best I've tried and I've tried a LOT.
Got this because I saw it all over my feed and figured why not. Been using it about 5 weeks. It doesn't sting or make my face red like retinol does, which was my main worry. My skin feels softer and the crepey texture on my cheeks has improved. Not dramatic but definitely noticeable when I touch my face. The pump is nice, you get exactly the right amount and nothing goes to waste.
I bought this on impulse. Glad I did. I'm 61 and have a lot of sun damage on my neck and chest. I've been putting it there as well as my face. About 6 weeks in the lines on my chest look less deep and the skin feels thicker somehow. My face looks less tired. Product itself is worth it.
What sold me were the ingredients! It has multiple active ingredients that go beautifully on my face! It's lightweight and really hydrating! It helps with fine lines and wrinkles as well. Renewa, you've earned a fan!
I have rosacea and sensitive skin so I patch tested first. No reaction at all. Been using it a month now. My redness is actually calmer and my skin feels more balanced, less oily in some spots and less dry in others. It's very gentle. I don't have a lot of wrinkles yet but the fine lines under my eyes look softer. I like that the ingredient list isn't a mile long. Going to keep using it.
I've had this about two months. I use it right after washing my face and then glide my device on top a few nights a week. The texture is thin and a little goes a long way, I'm still on my first bottle. My jawline area feels firmer and my skin just looks more even. The packaging is beautiful but I wish the bottle was clear so I could see how much is left.
I'm 3 months in and here's my take. Weeks 1 to 3, nothing much except my skin felt nice. Weeks 4 to 8, brighter, smoother, less blotchy. Now, my neck looks firmer and people have commented that I look rested. It's not a facelift in a bottle and anyone who says that about any serum is lying. But it does what a good serum should do and I'm on autoship now so I don't run out.
Frequently Asked Questions
Most serums treat the surface so it never touches the real cause of dryness, dullness or wrinkles and fine lines for changing menopausal skin. RenewaCell targets the three biological changes that cause quicker aging in menopausal skin: the breakdown in cell-to-cell communication, the depletion of cellular energy, and the acceleration of collagen loss that menopause triggers. Exosomes, Peptides, and NAD+ absorb into the deeper layers of skin to work at the cellular level where the skin aging actually starts.
Exosomes are tiny messenger molecules your skin cells use to communicate with each other to coordinate collagen production, moisture retention, and cellular repair. Think of them as biological text messages between cells. RenewaCell uses Goji Stem Cell Exosomes (Lycium Barbarum Callus / Cell Culture Extract) to restart the cell communication that menopause disrupts.
Peptides are short chains of amino acids, the building blocks your skin uses to produce collagen and elastin. RenewaCell's Peptides (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7) signal your skin to go into collagen-rebuilding mode, producing firmer, denser, more lifted skin.
NAD+ (Nicotinamide Adenine Dinucleotide) is the molecular fuel inside every skin cell, it powers DNA repair, collagen synthesis, and cellular energy production. By menopause, levels have dropped by nearly 50%. When restored, skin firms up, lines visibly reduce, and the glow that disappeared during menopause starts coming back.
Yes. RenewaCell was specifically formulated for the sensitivity that comes with menopausal skin changes. It contains no retinol, no harsh actives, no parabens, and no fragrance. The Peptides deliver collagen-rebuilding results comparable to retinol but without a single day of burning, peeling, or irritation.
Yes, and we recommend it. Apply 2 to 4 drops of RenewaCell first, then use RenewaLift immediately after. The device's Sonic Vibration helps the serum absorb deeper into the skin, and the EMS and LED therapies work synergistically with the Exosomes and Peptides for enhanced results.
Most women notice skin feeling softer, calmer, and more hydrated within the first week. Visible improvements in radiance and firmness typically appear between weeks 2 and 4. Full structural results like visibly denser skin, and significantly softer lines develop with consistent daily use over 6 to 8 weeks. Individual results vary.
Yes. RenewaCell layers well with your existing routine. Apply it to clean skin first, before any other serums, moisturizers, or SPF. It works alongside vitamin C, niacinamide, peptide serums, and hyaluronic acid without conflict. If you use any strong actives, applying RenewaCell first allows the Exosomes, Peptides, and NAD+ to absorb fully before layering anything else on top.
RenewaCell is built around three unique categories of ingredients and then a handful of supporting ingredients that amplify how well the main ingredients work. Exosomes (Lycium Barbarum Callus / Cell Culture Extract) restart the cell-to-cell communication menopause disrupts and signals your skin to produce collagen, retain moisture, and repair the damaged skin barrier again. Peptides (Palmitoyl Tripeptide-1 + Palmitoyl Tetrapeptide-7) are clinically proven to rebuild collagen deep in the skin to visibly firm the jawline, fill deep wrinkles and restore skin density while being gentle and effective for sensitive menopausal skin. NAD+ (Nicotinamide Adenine Dinucleotide) restores the cellular energy that drops by 50% during menopause to hold moisture, increase elasticity and smooth wrinkles.
On clean dry skin, apply 2 to 4 drops and gently massage in. Follow with moisturizer or SPF. For best results use daily in the morning, evening, or both. Consistent daily use produces the most visible changes.
Yes. RenewaCell absorbs quickly and leaves no residue, making it an effective hydrating base before makeup application.
Yes, RenewaCell is backed by a 100-Day Money-Back Guarantee. If you don't see a visible difference in your skin contact us within 100 days of delivery for a full refund. View our full Returns & Refund Policy.
Yes, we offer free worldwide shipping on all orders over $99.
After just four weeks of using RenewaCell Serum, I've been amazed by the difference in my skin. As a double-board certified dermatologist, I'm selective about the products I use and recommend, which is why l'm particularly impressed by RenewaCell's combination of exosomes, peptides, and NAD+. RenewaCell is one of those rare products that has earned a permanent place in my skincare routine.